despite：despite书面用词，指不受某事或某种原因的阻碍，语气轻于in spite of。
despite of：spite of在这些词中语气最强，可与despite换用，口语或书面语中均可使用。
扩展资料
Despite the power cuts, the hospital continued to function normally.
尽管供电中断，医院继续照常运作。
Despite her earnest efforts, she could not find a job.
尽管她已尽心竭力，但是仍然找不到工作。
Despite his cries, no one came to his assistance.
尽管他喊叫，却没有人来帮助他。
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